Researchers induce cancer cells to 'commit suicide' with a self-produced bacterial toxin

https://phys.org/news/2023-07-cancer-cells-commit-suicide-self-produced.html

For the first time in the world researchers at Tel Aviv University have encoded a toxin produced by bacteria into mRNA (messenger RNA) molecules and delivered these particles directly to cancer cells, causing the cells to produce the toxin—which eventually killed them with a success rate of 50%.

59 points · 4 comments · view on lemmy.world

4 Comments

Teal@kbin.social · 7 pts · 3y

This sounds promising! Killing cancer while leaving other cells alone is some seriously good news.

kevinbacon@lemmy.world · 6 pts · 3y

mRNA is a hot topic for some portion of the population lol

mohKohn@kbin.social · 2 pts · 3y (1 reply)

crisper-cas9!

Theranostics is a great word.

Since this seems to rely on the immune system to deliver the therapy anyway, I'm wondering how it's outperforming whatever mechanism the immune system would use instead.

Narrrz@kbin.social · 2 pts · 3y

I'm guessing immune cells deliver a signal to trigger apoptosis, but cancer cells usually mutate to quash that mechanism or break its function somehow.