Looking to make a rosmary alcohol tincture to investigate the alleged serotonin, dopamine, norepinephrine, and GABA A activity reported in mice.
Would a medicinal dose of fresh rosmary equate to 1 medicinal dose of alcohol extract or would the extract from 1 medicinal dose of fresh rosmary be a lot more potent? And if so, how do I determine how much is safe for human consumption?
Also, how would I determine the required ratio of 50-70% alcohol to distilled water? I'd like to have a tincture dosable in 1 drop.
2 Comments
MysteriousSophon21@lemmy.world · 1 pts · 1y
Please don't self-experiment with homemade extracts targeting neurotransmitters - the jump from mouse studies to human application is HUGE and potentially dangerus without proper pharmacokinetic testing.
TheModernDiogenes@lemmy.world · 1 pts · 1y
Can someone please give me legitimate criticism instead of downvoting? Yes, I'm an amateur, but it's based on peer-reviewed PubMed studies on the therapeutic potential of rosmary and it's terpenes and phytochemicals, not homeopathic bullshit, the medical science is there, I just don't have much organic chemistry experience.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7491497/