YSK that psilocybin, the active ingredient in magic mushrooms, is 50% less toxic than caffeine.

caffeine only needs 190 mg per kilogram of body weight to have a 50/50 chance of killing you, whereas you would need 280 mg per kilogram of body weight of psilocybin.

caffeine

psilocybin

15 points · 26 comments · view on lemmy.world

26 Comments

Agent641@lemmy.world · 6 pts · 1y (17 replies)

I want to do the 25 gram trip then.

nebulaone@lemmy.world · 1 pts · 1y
[ removed ]
Varyk@sh.itjust.works · 1 pts · 1y (15 replies)

go for it.

Physiologically safe, FDA recommended, non-habit-forming.

Sturgist@lemmy.ca · 5 pts · 1y (10 replies)

@Agent641@lemmy.world

I would recommend against it. While 25g of MUSHROOMS doesn't contain enough psilocybin to be anything close to lethal, it does contain enough to potentially be an extremely bad time. As someone who got stoned watching Ferris Bueller's Day Off and accidentally continued snacking on the almost 28g of mushrooms left in the bag....hard pass. Never again.

Varyk@sh.itjust.works · 2 pts · 1y (9 replies)

@Agent641@lemmy.world

Setting is important and that sounds like a terrible movie to do mushrooms on, especially with the creepy mannequin in the beginning.

That said, I think if people are following general recommended procedures, they should try magic mushrooms.

magic mushrooms are physiologically safe, mind-broadening, non-habit forming, even therapeutically recommended by the FDA.

if you're texting while driving you can crash your car, but that doesn't mean you should never drive.

especially if you want to go somewhere.

Sturgist@lemmy.ca · 1 pts · 1y (8 replies)
[ removed ]
Varyk@sh.itjust.works · 1 pts · 1y (7 replies)

I also endorse responsible consumption.

this is why I made the post, to address common forms of alarmism concerning psychedelic mushrooms.

Sturgist@lemmy.ca · 2 pts · 1y (6 replies)

Ok cool. It just seems like you're glossing over the actual cause of the bad trip. It had nothing to do with the movie.

Varyk@sh.itjust.works · 0 pts · 1y

glossing over? by directly addressing your concerns?

I wasn't with you when you took that fateful trip, so I am not absolutely certain what went wrong for you. I'm responding to the story you've provided.

Setting is very important during a psychedelic trip, and putting on a loud, emotionally aggressive movie that starts with a creepy mannequin is not a psychedelics setting I would ever recommend.

you are making very strong recommendations to other people based on your single anecdotal experience.

nebulaone@lemmy.world · 2 pts · 1y (3 replies)
[ removed ]
Varyk@sh.itjust.works · 1 pts · 1y (2 replies)

You're conflating LSD and psilocybin, two completely different chemicals with entirely different risk profiles.

you are also making alarmist claims without any evidence.

LSD is physiologically and psychologically dangerous.

psilocybin is physiologically safe and is only a psychological risk if you already have complicating factors.

https://nida.nih.gov/research-topics/psilocybin-magic-mushrooms#%3A%7E%3Atext=The+risk+of+mental+health%2Cresearch+on+psilocybin+is+low.

please provide evidence if you want to make such far-reaching claims conflating two entirely different chemicals.

Laser@feddit.org · -2 pts · 1y (1 reply)

you are also making alarmist claims without any evidence.

LSD is physiologically and psychologically dangerous.

Ok dude.

Varyk@sh.itjust.works · 1 pts · 1y

okay.

genuineparts@infosec.pub · 5 pts · 1y (1 reply)

Makes for a very different morning tho...

Varyk@sh.itjust.works · 2 pts · 1y

Heck yeah it does.

QuoVadisHomines@sh.itjust.works · 4 pts · 1y (1 reply)

The LD50 isn’t the concern rather it is the psychological harm that can come about from bad trips.

Varyk@sh.itjust.works · -1 pts · 1y

toxicity is a concern.

psychological risks concerning mushrooms are extremely low.

much lower than the movies or rumors online might make you think.

https://nida.nih.gov/research-topics/psilocybin-magic-mushrooms#%3A%7E%3Atext=The+risk+of+mental+health%2Cuse+outside+of+clinical+settings.

nesc@lemmy.cafe · 3 pts · 1y (3 replies)

Pointless fact.

okwhateverdude@lemmy.world · 5 pts · 1y (1 reply)

It isn't pointless if you wanted to poison someone with psilocybin and had a misconception about the LD50. It'd be a really useful, helpful fact, actually. So, uhh. Thanks OP. I almost made a terrible mistake.

dirtydocmark@sh.itjust.works · 2 pts · 1y
[ removed ]
Varyk@sh.itjust.works · 3 pts · 1y

I appreciate your pointless comment.

QueenHawlSera@sh.itjust.works · 2 pts · 1y (1 reply)

I should buy some shroom chocolate

Varyk@sh.itjust.works · 1 pts · 1y

chocolate was actually my first introduction to shrooms.

it was pretty great. I laughed for a very long time with a friend, and was like "yea. this is good."

and I didn't even know how safe it was then, haha.

Kolanaki@pawb.social · 2 pts · 1y

Will it help keep me awake if I take twice as much as usual, then?

Geodad@lemmy.world · 0 pts · 1y (5 replies)
[ removed ]
Varyk@sh.itjust.works · 1 pts · 1y (4 replies)

That is the point of the post, thank you for your support.

Geodad@lemmy.world · 1 pts · 1y (3 replies)
[ removed ]
Varyk@sh.itjust.works · 1 pts · 1y (2 replies)

"disinfo": which part of the ld50 do you take issue with?

again, you are arguing in support of this post that notes the low toxicity of psilocybin.

you'll have to provide proof or your comments will be removed.

Geodad@lemmy.world · 1 pts · 1y (1 reply)
[ removed ]
Varyk@sh.itjust.works · 1 pts · 1y

you want details.

details are not at all "disinformation", which is the deliberate attempt to mislead or deceive.

you simply want more information, which is why I made this post, including the two links to the specific numbers for those interested in the details.

the ld50 of caffeine is about 150 mg/kg, the ld50 of psilocybin is 293 mg/kg.

hence the post letting people(like you) know that caffeine is about twice as toxic as psilocybin.

plenty of people are uninformed as to the toxicity of magic mushrooms, and I want people to know that they are physiologically safer than the active ingredient in soda or tea or whatever caffeinated beverage you prefer.