Generative design of novel bacteriophages with genome language models

https://www.biorxiv.org/content/10.1101/2025.09.12.675911v1.full

Bonkers preprint, the guys generated phage genomes with AI, synthesized them, and some were actually functional viruses capable of infecting E. coli.

10 points · 4 comments · view on lemmy.world

4 Comments

plyth@feddit.org · 2 pts · 337d (2 replies)

This is fascinating and frightening. It's only a matter of time until there is the next lockdown.

crt0o@discuss.tchncs.de · 4 pts · 337d

Well the models were trained on bacteriophages, so it's pretty much impossible that the viruses could be human pathogens, still scary af though lol

PhilipTheBucket@piefed.social · 3 pts · 337d

Bird flu is still out there too, and it seems likely that by the time it figures out humans, the US public health apparatus will be basically destroyed.

Ever lived through a plague in the middle ages? Would you like to?

PhilipTheBucket@piefed.social · 2 pts · 337d

What's the worst that could happen