Intro:
In a major advance in genetics, scientists at Northwestern University have uncovered what researchers describe as a hidden second layer of human DNA. By mapping how the genome folds and shifts inside living cells, the team has revealed how the physical structure of DNA helps control gene activity.
The research, conducted with the 4D Nucleome Project and published in Nature, offers a new understanding of how genetic instructions operate beyond the DNA sequence itself.
Conclusion & research article link:
By linking DNA folding, chromatin loops, and gene regulation, the study provides a more complete picture of how genetic instructions function inside cells. Scientists report that this new perspective could lead to improved diagnostic tools and more precise therapies based on genomic structure.
The findings mark an important step toward understanding how this hidden second layer of DNA influences human health and disease.
13 Comments
dumbass@piefed.social · 35 pts · 183d
We got DNA DLC before GTA 6.
NigelFrobisher@aussie.zone · 3 pts · 183d
Dammit I just made this connection and you got there just lol
joeldebruijn@lemmy.ml · 27 pts · 183d
I find it truely amazing but a "hidden second layer" would be like a palimpsest, data-within-data.
In this case it seems more like "besides the data also the mechanics of the storage play a crucial and far bigger role then anticipated".
But headlines etc etc
abc@moist.catsweat.com · 17 pts · 183d
But that's just epigenetics, isn't it? I know that's been heavily researched for at least a decade, since that's when i learnt about it at uni
ramble81@lemmy.zip · 3 pts · 182d
village604@adultswim.fan · 1 pts · 182d
That XKCD isn't relevant here.
Berengaria_of_Navarre@lemmy.world · 16 pts · 183d
Do I need to bother reading this, or is it just a journalist misunderstanding epigenetics?
frongt@lemmy.zip · 12 pts · 183d
From the paper OP linked:
Yes.
Berengaria_of_Navarre@lemmy.world · 5 pts · 182d
I thought as much.
finallymadeanaccount@lemmy.world · 7 pts · 183d
DNB?
IcedRaktajino@startrek.website · 10 pts · 183d
Only if the USB Implementation Forum doesn't get a chance to name it. Otherwise, it'd be something like DNA 3 2.0 Super Speed
GargleBlaster@feddit.org · 5 pts · 183d
Should be based on this Nature paper. Haven't read it yet though.
misk@piefed.social · 3 pts · 183d
This YouTube playlist has visualisations of how this works. It’s pretty neat.