I saw a study somewhere about this, something like it will create a larger spike at first but a shorter halflife . Since it’s a daily pill, it won’t make much difference. Maybe protect your liver more.
That is accurate, but it also has higher bioavailability when taken sublingually so you get more estrogen for the same number of pills. Its easier on the liver that way, but it requires you to take it multiple times per day.
I take mine every 12 hours now. I did every 8 hours when I was on a dose that was divisible by three. The spikes haven't been an issue for me. Biology works in averages.
Yeah it doesn't actually matter which way you take it, just that it is consistent. Won't actually help your liver more either way since the stuff that can harm your liver is actually one of metabolites of the medication made when your liver turns it into usable estrogen not the medication itself.
People worried about their liver should be doing patches or injections if possible.
i can personally recommend: letting it melt under the tongue (i think it helps if you powder it first), then drinking a large glass of water. much easier to process for the body that way. everything in your body uses water as a solvent, you do not want to run out of that!
12 Comments
EggInDisguise@lemmy.blahaj.zone · 45 pts · 31d
Ask neither permission, nor forgiveness.
Be you, they'll adjust or not.
queermunist@lemmy.ml · 24 pts · 31d
NO!
You're supposed to let the pill melt under your tongue, not wash it down with a glass of water.
💕
dangling_cat@piefed.blahaj.zone · 9 pts · 31d
I saw a study somewhere about this, something like it will create a larger spike at first but a shorter halflife . Since it’s a daily pill, it won’t make much difference. Maybe protect your liver more.
queermunist@lemmy.ml · 9 pts · 31d
Yeah, it's for liver health, but also that rollercoaster effect can be mitigated by taking a smaller sublingual dose multiple times a day.
hildegarde@lemmy.blahaj.zone · 8 pts · 31d
That is accurate, but it also has higher bioavailability when taken sublingually so you get more estrogen for the same number of pills. Its easier on the liver that way, but it requires you to take it multiple times per day.
I take mine every 12 hours now. I did every 8 hours when I was on a dose that was divisible by three. The spikes haven't been an issue for me. Biology works in averages.
TessaRekt@lemmy.dbzer0.com · 5 pts · 31d
Yeah it doesn't actually matter which way you take it, just that it is consistent. Won't actually help your liver more either way since the stuff that can harm your liver is actually one of metabolites of the medication made when your liver turns it into usable estrogen not the medication itself.
People worried about their liver should be doing patches or injections if possible.
thethunderwolf@lemmy.dbzer0.com · 2 pts · 16d
or gel
gandalf_der_12te@lemmy.blahaj.zone · 2 pts · 29d
i can personally recommend: letting it melt under the tongue (i think it helps if you powder it first), then drinking a large glass of water. much easier to process for the body that way. everything in your body uses water as a solvent, you do not want to run out of that!
queermunist@lemmy.ml · 2 pts · 29d
I go to sleep with it under my tongue, which seems to work pretty well.
I also have a daily siesta so that lets me dose every 12-ish hours.
tlekiteki@lemmy.dbzer0.com · 23 pts · 31d
thoughtfuldragon@lemmy.blahaj.zone · 10 pts · 30d
You can do it I decided
gandalf_der_12te@lemmy.blahaj.zone · 7 pts · 29d
you gotta find your own purpose in life, don't let other people tell you what is allowed and what isn't.
Pandantic@midwest.social · 6 pts · 29d
Who cares?! DO IT ANYWAY!!