MrFloppy

u/MrFloppy@lemmy.world
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If Nestlé hadn’t acquired “Aimmune Palforzia” in 2020, things would certainly have turned out differently.

Here is a rough description of how the therapy worked.
You can find detailed PDFs on this topic by searching for “Palforzia therapy plan.”

Challenge testing at the clinic
At the clinic, tests are conducted using a placebo and “peanut powder in chocolate pudding” to determine how much peanut the child can tolerate. (The emergency kit must always be on hand)

Build-up phase
The first therapy dose of “peanut powder in chocolate pudding” is administered at the clinic; every subsequent increase in the dose level takes place under the supervision of the attending physician. (The emergency kit must always be on hand.) During the 14 days between each increase, the parents mix the peanut powder into chocolate pudding or applesauce daily (no medical supervision required). If an allergic reaction occurs, the emergency kit must be used. One day per week may be skipped.

Dose level / Daily dose / Duration of the dose:

  1. / 3 mg / 2 weeks
  2. / 6 mg / 2 weeks
  3. / 12 mg / 2 weeks
  4. / 20 mg / 2 weeks
  5. / 40 mg / 2 weeks
  6. / 80 mg / 2 weeks
  7. / 120 mg / 2 weeks
  8. / 160 mg / 2 weeks
  9. / 200 mg / 2 weeks
  10. / 240 mg / 2 weeks
  11. / 300 mg / 2 weeks

The maintenance phase follows the build-up phase
Instead of 300 mg of peanut powder, 1–2 sugar-coated peanuts (M&Ms, Nic Nac, or natural without coating) can also be used as the maintenance dose (no medical supervision required)

After 12 months, the final challenge test is conducted at the clinic
There, using a placebo and peanut powder in chocolate pudding, they test how much peanut the child can tolerate.

After the final challenge test, the clinic recommends how many sugar-coated peanuts the child should consume per week to maintain immunity.

Perhaps the most straightforward solution would be to modify "tiles 1-3" so that they also display the content text. And if someone does not want this text, they can select "Full content, max. lines: 0"

With the new update it works much better. General text size 1,0. Post size XL/L and comment size L/M looks much better (like the alpha version). Thanks a lot!

on Fr(ule)ance 🇨🇵🔥 · c/196 · 3 pts · 1y

It's the same tactic as getting rid of pigeons. You don't destroy the eggs, you make them unusable (plaster eggs). Because destroyed eggs are immediately replaced by the pigeons with functioning eggs.

In Europe, we make similar mistakes: the right wing promotes the right, the left wing berates the right wing and the media constantly report on the absurdities of the right wing or reinforce some right-wing theme. As a result, the right wing gets all the media attention and people wonder why the right wing is gaining strength.