Great point, plus the body can make glucose on its own if it's needed, so those keto people still have glucose, it's just 99.9% of the body is burning fat, so there isn't much demand for that glucose.
Bonus fact: the emerging literature is linking long term neurodegenerative diseases (dementia, Alzheimer's, parkinson's, etc) to impaired brain glucose metabolism... I.e the more insulin resistant someone becomes the more energy starved their brains are, but even in those people ketones feed the brain without impairment
Carbohydrates drive fat, if you want to lose weight, reduce your carbs or cut them out completely.
This literature survey is basically talking about the virtues of fgf 21 activation, which happens in a high glucose diet with low protein inputs. Inputs. However, they did not look at low glucose diets.
Yeah, bread is carbohydrates and your body turns all carbohydrates into glucose in your blood, however high blood sugar isn't great so the body releases insulin to get blood sugar back to normal.. the insulin forces your fat cells to take in all this new glucose (that's how it lowers your blood sugar)...
some small human studies, people who ate a protein-restricted diet for several weeks lost weight and fat mass, and saw improvements in their fasting blood sugar—even though people on these diets tended to eat more calories.
Fgf21 will do that, but is it a long term benefit in humans? We have other ways of reducing human blood sugars while eating more calories (keto).
Conversely, a high-protein, low-carbohydrate diet was recently shown to be less effective than a moderate-protein diet in lowering blood glucose, improving glucose tolerance, and promoting prediabetes remission.[38]
And if you follow reference 38 you will see low carb is 45% energy from carbs.... No where near a fat based metabolism, which is what most people will think from "low carb"
These seemingly contradictory studies leave many wondering what the optimal amount of dietary protein is for healthy aging
It's not contradictory, the epidemiology they use and the one off 45% energy from glucose study they call low carb - don't control for underlying metabolism. Yes in the context of a high glucose diet consuming low protein will activate fgf21 increasing metabolic rates by 20ish% showing blood glucose improvements... But that isn't the only lever, and quite frankly if you want better control of blood glucose maybe a glucose free diet should be considered by the authors.
There isn't really any controversy with the company or the products. one of the co-founders fail people's political purity testing, but the products are solid.
it's an extremely hot take to call them a nazi because you disagree on one person's political viewpoints on immigration, and try to purity test a great open source project because of it.
Yeah but we evolved for 2.5 million years of survival before bread was invented.....
Great point, plus the body can make glucose on its own if it's needed, so those keto people still have glucose, it's just 99.9% of the body is burning fat, so there isn't much demand for that glucose.
Bonus fact: the emerging literature is linking long term neurodegenerative diseases (dementia, Alzheimer's, parkinson's, etc) to impaired brain glucose metabolism... I.e the more insulin resistant someone becomes the more energy starved their brains are, but even in those people ketones feed the brain without impairment
yeah, thats rough
Sure, they have lots of honeyed things to say! get a CGM and wear it for two weeks, it's eye opening!
Because your so biased you have subconsciously dehumanized people you disagree with
At least the photo isn't ai generated
Carbohydrates drive fat, if you want to lose weight, reduce your carbs or cut them out completely.
This literature survey is basically talking about the virtues of fgf 21 activation, which happens in a high glucose diet with low protein inputs. Inputs. However, they did not look at low glucose diets.
Yeah, bread is carbohydrates and your body turns all carbohydrates into glucose in your blood, however high blood sugar isn't great so the body releases insulin to get blood sugar back to normal.. the insulin forces your fat cells to take in all this new glucose (that's how it lowers your blood sugar)...
Therefore - bread makes you fat.
I eat beef!!!!!!
This a a great read
Fgf21 will do that, but is it a long term benefit in humans? We have other ways of reducing human blood sugars while eating more calories (keto).
The actual papart they are talking about https://doi.org/10.1016/j.cpblue.2026.100079
And if you follow reference 38 you will see low carb is 45% energy from carbs.... No where near a fat based metabolism, which is what most people will think from "low carb"
It's not contradictory, the epidemiology they use and the one off 45% energy from glucose study they call low carb - don't control for underlying metabolism. Yes in the context of a high glucose diet consuming low protein will activate fgf21 increasing metabolic rates by 20ish% showing blood glucose improvements... But that isn't the only lever, and quite frankly if you want better control of blood glucose maybe a glucose free diet should be considered by the authors.
Carbohydrate addiction will do that!
It's nice to see a headline admit the data was from mice
This is much better then choosing Antarctica!
No... it has been about mullvad being a great browser that just acts like a browser.
and i've addressed why that hot take is just a whataboutism and purity testing doesn't belong in open source discussions.
Same to you buddy! This is my thread your badgering me on.
and they cited a article calling the cofounder a nazi.
I don't care about the cofounders personal politics. The product is open source, its solid, and does a excellent job.
now you have moved the goalposts from mullvad, to one of its founders using personal money, now to a political party that isn't involved in mullvad.
does any of this impact the open source project? no.
There isn't really any controversy with the company or the products. one of the co-founders fail people's political purity testing, but the products are solid.
it's an extremely hot take to call them a nazi because you disagree on one person's political viewpoints on immigration, and try to purity test a great open source project because of it.
That's a fun hot take, regardless the open source browser they sponser is amazing and it's exactly what I want out of the box.