Folks have already pointed out the whole "multiple teams of sled dogs" thing.
The dogs also weren't delivering vaccine. They were delivering diphtheria antitoxin, which is a treatment for diphtheria, not an inoculation. The kids were already sick.
There was technically a vaccine for diphtheria then (it was invented in 1923, two years before this epidemic), but it wouldn't have saved anyone who'd already caught the infection.
Fuck that. Balto's owner was the asshole. Balto himself and his team were sold and spent years malnourished and chained to a sled in a freak show wondering what they did wrong, and when they were finally "rescued" they wound up in a zoo. Well fed, but in cages while people gawked at them. Balto watched the rest of his team die one by one until he himself died blind and paralyzed.
Togo spent the rest of his life with his family. Neither dog knew they were famous or why, but Togo knew he was loved.
I think Togo won in the end, because Balto and his sled team basically became freak show animals and later live museum exhibits, chained and starving, like they weren't living creatures at all. They were later rescued and ended their days as zoo animals. After Balto died he was stuffed and put in a museum.
Meanwhile Togo and his team went on tours, were given gold medals, continuing their lives as sled dogs and Togo got to retire in a nice kennel where he was bred and lived well until he was euthanized at the age of 16 due to health complications.
Don't feel bad for Togo. He may have been largely forgotten to history, but he sure as shit won the life lottery compared to Balto.
You'll have to sail the high seas. It's a Disney movie but they have "put it in the vault"
Which upsets me considerably, because it's an amazing film that made me weep. Literally, fucking, weep. Wailing and gnashing of teeth type sobbing.
Point being, it's a great movie with a happy ending for the dogs, so you don't have to worry about that.
Highly recommended.
Alternatively, you could watch The Great Alaskan Race, which tells the same, more accurate version on a much lower budget. My late-girlfriend was the wardrobe designer on it, so I feel obligated to mention it, even though it's a bit rough around the edges.
The sled dog team led by Balto didn't deliver vaccines. The vaccine for Diphtheria didn't exist in 1925.
They delivered diphtheria antitoxin serum which was the only treatment at the time.
The image has a good sentiment though. The Florida change is just more undermining of public schools to push private charter school enrollment. These bozos in our government voted in vouchers to directly subsidize the businesses they themselves are invested in.
It was initially discovered on the other side of the planet in a french lab in 1923. It wasnt widely adopted until the 30s. But yeah it technically did "exist". In hindsight I should have just said it wasn't available.
To be fair, the covid vaccine isn't a vaccine. It's an experimental genetic therapy (created by a corporation that would happily murder you for profit).
I'm pretty sure you misunderstood the way these vaccines work - no judgment, media is ass these days - so let me clear it out for you.
mRNA vaccines (Pfizer, Moderna) give cells a piece of RNA (ribonucleic acid) coding the spike proteins of SARS-CoV-2, the virus causing COVID-19. mRNA normally serves as a translation layer: it simply comes to rRNA, lays down and says "we make THIS". And there's the end of it. No long-term changes are made, the cell just produces respective proteins for a while, before new genuine orders come along.
In this process, spike proteins of SARS-CoV-2 are being created, are being recognized by the immune system as something that is clearly not yours, destroyed and remembered. Other than this response typical for any vaccine or illness, nothing else ultimately changes.
Vector vaccines (Johnson & Johnson, Sputnik V) put the spike-coding sequence into another virus that is otherwise harmless. Then this virus enters your body with a shot, and then much the same thing occurs.
To be clear: viruses do these kinds of things all the time. SARS-CoV-2, that very virus causing COVID-19, does this too, except it instructs cells to replicate the entire thing, so that it could infect other cells and proliferate. In this way, such vaccines are no different than just getting infected, with one major difference in that you don't get sick in the first place and don't have random dangerous code replicate all around your body. Harmless spike proteins get formed in a controlled manner and quantity - and that's it.
Even if you were an evil billionaire wishing to decimate human population or something, you'd have very hard time making something RNA-based that somehow persists in the body and also doesn't reveal the effects for a long while. Easier to do with vector-based vaccines, but very hard to make it unnoticeable, either.
A vaccine was once "a weakened form of the pathogen, introduced so the body could create antigens without actually becoming ill". Your technobabble (sorry) sounds like something different.
Yes, because we knew no better. Now we can be more precise and replicate specifically the parts immune system can recognize that are not harmful to us. If anything, we made vaccines safer than they were before.
It's like saying solar panels are technobabble because we once gathered nearly all energy by burning wood or coal. Sure, we did, but why do it now? We know better options.
Besides, it takes school-level knowledge of biology to understand the reasoning behind these vaccines. They rely on the knowledge we had for many decades now; it was only hard to produce such RNA sequences at scale and to meet all the standards while doing so. Now we can do this, and it makes no sense to do otherwise.
Traditional vaccines are more dangerous and, at their best, just as efficient. Besides, they typically take longer to develop and test, and time was a pressing issue. Some traditional-style vaccines got eventually rolled out, but they did not outperform the alternatives, and so they didn't gain much traction.
So, overall, the biggest and most pressing issue with mRNA/vector-based vaccines is lack of literacy among the people who fear it.
Because I studied well at school (which is enough as a prerequisite), and also happen to have a major in microbiology, which is related to what we're talking about.
If there are things in particular that you are skeptical about, let me know.
It is, which is why I said "related" as a hedge - and also mentioned that you don't have to be any kind of biologist if you just listened to your biology classes back in the day.
Basic education is enough to understand, in general terms, how it works.
On my end, as a microbiologist, I had extensive training on viruses and the way most of them work is very similar. I can confirm that the vaccine doesn't do anything SARS-CoV-2 itself wouldn't.
So, what makes you skeptical of these vaccines? Or are you trolling around?
A vaccine is a substance used to stimulate the production of antibodies and provide immunity against a disease. The COVID-19 vaccines do exactly this.
It trains your body to fight the disease. The methods and techniques are different but the fundamentals are still the same. It's ridiculous to think that its permanent genetic modification.
The only "genetic modification" that I understand happening is the modification to our immune systems being able to fight diseases much better than before. Eventually getting rid of diseases entirely.
But I guess people thought that was stupid, so now we have measles again like its 1953
Traditional vaccines work, because your immune cells learn about the "key" they need, to open up the virus and destroy it.
mRNA is basically just shipping the "keyhole" instead of the whole virus organism for your body to learn the pattern. So no crazy "gene therapy". It is just more precise.
Like, back in the day, people used maps to navigate. Now you use crazy GPS space stuff to do the same. Just better technology for the same end.
More of an analogy then a story. Feel free to do some independent research. Look at some creditable peer reviewed studies. There are mounds of information out there that support both traditional and the newer mRNA vaccines.
76 Comments
cinnabarfaun@lemmy.world · 110 pts · 336d
Folks have already pointed out the whole "multiple teams of sled dogs" thing.
The dogs also weren't delivering vaccine. They were delivering diphtheria antitoxin, which is a treatment for diphtheria, not an inoculation. The kids were already sick.
There was technically a vaccine for diphtheria then (it was invented in 1923, two years before this epidemic), but it wouldn't have saved anyone who'd already caught the infection.
Swedneck@discuss.tchncs.de · 17 pts · 335d
people really do not understand what vaccines do
justcallmelarry@lemmy.dbzer0.com · 4 pts · 334d
Yuh-huh! They give autism! /s
the_riviera_kid@lemmy.world · 93 pts · 336d
Thats right, because Togo did it. Balto was just given all the credit becuse he did the final leg.
Sanctus@lemmy.dbzer0.com · 44 pts · 336d
Well you're right. Balto didn't do it.
thespcicifcocean@lemmy.world · 35 pts · 336d
Fuckin stolen valor asshole dog
ceenote@lemmy.world · 53 pts · 336d
He was a good boy, don't blame him for what people did.
thespcicifcocean@lemmy.world · 14 pts · 336d
Oh sorry, I'm biased against huskies in general. I think they're all assholes.
ceenote@lemmy.world · 11 pts · 336d
They are, but dogs can be assholes and good at the same time. People, on the other hand...
if_only@sh.itjust.works · 26 pts · 336d
Fuck that. Balto's owner was the asshole. Balto himself and his team were sold and spent years malnourished and chained to a sled in a freak show wondering what they did wrong, and when they were finally "rescued" they wound up in a zoo. Well fed, but in cages while people gawked at them. Balto watched the rest of his team die one by one until he himself died blind and paralyzed.
Togo spent the rest of his life with his family. Neither dog knew they were famous or why, but Togo knew he was loved.
thespcicifcocean@lemmy.world · 15 pts · 336d
I actually didn't know that, fuck our species
Imgonnatrythis@sh.itjust.works · 10 pts · 336d
Goddammit. Why do even the good dog stories have sad endings. Every damn time.
Sonotsugipaa@lemmy.dbzer0.com · 20 pts · 336d
I don't quite remember the story, but I don't think Balto had much of a say in his portrayal
Nangijala@feddit.dk · 12 pts · 336d
I think Togo won in the end, because Balto and his sled team basically became freak show animals and later live museum exhibits, chained and starving, like they weren't living creatures at all. They were later rescued and ended their days as zoo animals. After Balto died he was stuffed and put in a museum.
Meanwhile Togo and his team went on tours, were given gold medals, continuing their lives as sled dogs and Togo got to retire in a nice kennel where he was bred and lived well until he was euthanized at the age of 16 due to health complications.
Don't feel bad for Togo. He may have been largely forgotten to history, but he sure as shit won the life lottery compared to Balto.
TheRealKuni@piefed.social · 6 pts · 336d
Also he finally got a pretty good movie starring Willem Dafoe.
Nangijala@feddit.dk · 3 pts · 336d
Haven't seen it, but I'll put it on my watch list! 👍
MysticEdge@lemmy.world · 1 pts · 335d
You'll have to sail the high seas. It's a Disney movie but they have "put it in the vault"
Which upsets me considerably, because it's an amazing film that made me weep. Literally, fucking, weep. Wailing and gnashing of teeth type sobbing.
Point being, it's a great movie with a happy ending for the dogs, so you don't have to worry about that.
Highly recommended.
Alternatively, you could watch The Great Alaskan Race, which tells the same, more accurate version on a much lower budget. My late-girlfriend was the wardrobe designer on it, so I feel obligated to mention it, even though it's a bit rough around the edges.
parody@lemmings.world · 2 pts · 336d
lol
buttnugget@lemmy.world · 25 pts · 335d
We have to draw a hard line with these traitors. Mandatory vaccination for everyone entering decent states from traitor states.
analog_fluffy@lemmy.zip · -21 pts · 335d
Are you a vaccine scientist?
DragonTypeWyvern@midwest.social · 8 pts · 335d
Are you a conscious being? Signs point to no.
analog_fluffy@lemmy.zip · -12 pts · 335d
Zing. And look, the mob likes you.
Watch out. You might just believe whatever your friends believe.
Alwaysnownevernotme@lemmy.world · 6 pts · 335d
Looks deeply into the eyes of 226 years of immunology.
"Friends, yes. Just.. friends."
Ghis@lemmy.world · 1 pts · 334d
It's called common sense, bud. Go back to r/conservative
buttnugget@lemmy.world · 7 pts · 335d
Who amongst us isn’t?
syreus@lemmy.world · 25 pts · 336d
The sled dog team led by Balto didn't deliver vaccines. The vaccine for Diphtheria didn't exist in 1925.
They delivered diphtheria antitoxin serum which was the only treatment at the time.
The image has a good sentiment though. The Florida change is just more undermining of public schools to push private charter school enrollment. These bozos in our government voted in vouchers to directly subsidize the businesses they themselves are invested in.
onslaught545@lemmy.zip · 9 pts · 336d
It did exist. It was developed in 1923.
syreus@lemmy.world · 4 pts · 335d
It was initially discovered on the other side of the planet in a french lab in 1923. It wasnt widely adopted until the 30s. But yeah it technically did "exist". In hindsight I should have just said it wasn't available.
Kolanaki@pawb.social · 4 pts · 335d
Just have the dog run farther 🤷♂️
untorquer@lemmy.world · 21 pts · 336d
Neither did Balatro
cdf12345@lemmy.zip · 11 pts · 336d
You joker
untorquer@lemmy.world · 7 pts · 336d
remember to spade and neuter your pets. o7
EmpathicVagrant@lemmy.world · 7 pts · 336d
Good reminder to give that game another chunk of my life.
FuckFascism@lemmy.world · 20 pts · 336d
DragonTypeWyvern@midwest.social · 2 pts · 335d
He actually had a very troubling social media presence on "The Chihuahua Question"
ryedaft@sh.itjust.works · 18 pts · 336d
They don't have sled dogs in Florida.
Zachariah@lemmy.world · 40 pts · 336d
soon they won’t have kids either
some_designer_dude@lemmy.world · 30 pts · 336d
Probably for the best… No child should have to live in Florida.
buttnugget@lemmy.world · 2 pts · 335d
Mandatory abortions for all right wingers in Florida.
LifeInMultipleChoice@lemmy.world · 13 pts · 336d
Feel bad joking about it but it sounds like a cutting cost program. Moving from No kids left behind to just no kids left
Rusty@lemmy.ca · 4 pts · 336d
Do they use sled alligators?
yeather@lemmy.ca · 3 pts · 336d
No, alligators are lazy, ambush predators that stalk and move slowly. Crocodiles are more versatile, faster, and have more stamina for sledding.
burntbacon@discuss.tchncs.de · 1 pts · 335d
Only at christmastime.
'Twas the night before Christmas An' all t'ru de house...'
knight_alva@lemmy.world · 11 pts · 336d
Been a while. Was it a vaccine? I thought it was penicillin he was hauling.
knight_alva@lemmy.world · 34 pts · 336d
Looked it up. We are both wrong. Apparently it was a specific antitoxin serum for diphtheria. Still not a vaccine but also not penicillin.
captainlezbian@lemmy.world · 10 pts · 336d
Makes sense. Unfortunately diptheria will be swelling soon
BanMe@lemmy.world · 7 pts · 336d
Antitoxin serum!? You gonna tell me what I should put in my kids bodies? Hell no! That's communisocialism
knight_alva@lemmy.world · 6 pts · 336d
Brother bear don’t treat me like I can read. Communowhatever is for hippies.
FreshParsnip@lemmy.ca · 11 pts · 336d
It was actually several different sled dogs that made the trip and Togo did the longest and most difficult part. There's a movie about Togo on Disney+
yermaw@sh.itjust.works · 10 pts · 336d
Listen, smart arse, ive never been deathly ill in all my life, so what was the point of getting all these vaccines?
Checkmate, big-pharma bootlickers.
WilloftheWest@feddit.uk · 5 pts · 336d
I’m not sure this is the case, but I like to imagine that the statue is polished from people petting it.
TropicalDingdong@lemmy.world · 3 pts · 336d
Pshhh. What do you mean? What u don't personally experience as being real isn't real.
Duh...
rabber@lemmy.ca · 2 pts · 336d
Alberta
Rusty@lemmy.ca · 1 pts · 336d
Nomorereddit@lemmy.today · -11 pts · 335d
Oh boy, shaming! Featuring, fall in line bich! And now including, not doing what i say is stupid!
Real take: all vaccines should come w free wifi.
Kage520@lemmy.world · 5 pts · 335d
I had a patient say to me "The only vaccine I ever got in my life was Polio, and I regret it. It was about to be eradicated from humanity!"
Dude totally doesn't get it.
InternetCitizen2@lemmy.world · 2 pts · 335d
Can mine make my dick bigger?
analog_fluffy@lemmy.zip · -40 pts · 336d
To be fair, the covid vaccine isn't a vaccine. It's an experimental genetic therapy (created by a corporation that would happily murder you for profit).
That's the facts.
InternetCitizen2@lemmy.world · 21 pts · 335d
analog_fluffy@lemmy.zip · 1 pts · 335d
Ok. Who should I listen to?
yistdaj@pawb.social · 15 pts · 336d
RNA vaccines may be relatively new, but they aren't genetic therapy. It does not get integrated into your DNA.
Plus, weren't there 3 covid vaccines? One of them used a more traditional method.
Allero@lemmy.today · 10 pts · 335d
I'm pretty sure you misunderstood the way these vaccines work - no judgment, media is ass these days - so let me clear it out for you.
mRNA vaccines (Pfizer, Moderna) give cells a piece of RNA (ribonucleic acid) coding the spike proteins of SARS-CoV-2, the virus causing COVID-19. mRNA normally serves as a translation layer: it simply comes to rRNA, lays down and says "we make THIS". And there's the end of it. No long-term changes are made, the cell just produces respective proteins for a while, before new genuine orders come along.
In this process, spike proteins of SARS-CoV-2 are being created, are being recognized by the immune system as something that is clearly not yours, destroyed and remembered. Other than this response typical for any vaccine or illness, nothing else ultimately changes.
Vector vaccines (Johnson & Johnson, Sputnik V) put the spike-coding sequence into another virus that is otherwise harmless. Then this virus enters your body with a shot, and then much the same thing occurs.
To be clear: viruses do these kinds of things all the time. SARS-CoV-2, that very virus causing COVID-19, does this too, except it instructs cells to replicate the entire thing, so that it could infect other cells and proliferate. In this way, such vaccines are no different than just getting infected, with one major difference in that you don't get sick in the first place and don't have random dangerous code replicate all around your body. Harmless spike proteins get formed in a controlled manner and quantity - and that's it.
Even if you were an evil billionaire wishing to decimate human population or something, you'd have very hard time making something RNA-based that somehow persists in the body and also doesn't reveal the effects for a long while. Easier to do with vector-based vaccines, but very hard to make it unnoticeable, either.
analog_fluffy@lemmy.zip · -2 pts · 335d
A vaccine was once "a weakened form of the pathogen, introduced so the body could create antigens without actually becoming ill". Your technobabble (sorry) sounds like something different.
Allero@lemmy.today · 5 pts · 335d
Yes, because we knew no better. Now we can be more precise and replicate specifically the parts immune system can recognize that are not harmful to us. If anything, we made vaccines safer than they were before.
It's like saying solar panels are technobabble because we once gathered nearly all energy by burning wood or coal. Sure, we did, but why do it now? We know better options.
Besides, it takes school-level knowledge of biology to understand the reasoning behind these vaccines. They rely on the knowledge we had for many decades now; it was only hard to produce such RNA sequences at scale and to meet all the standards while doing so. Now we can do this, and it makes no sense to do otherwise.
Traditional vaccines are more dangerous and, at their best, just as efficient. Besides, they typically take longer to develop and test, and time was a pressing issue. Some traditional-style vaccines got eventually rolled out, but they did not outperform the alternatives, and so they didn't gain much traction.
So, overall, the biggest and most pressing issue with mRNA/vector-based vaccines is lack of literacy among the people who fear it.
analog_fluffy@lemmy.zip · 0 pts · 335d
It's a nice story but I'm not buying it.
Why do you buy it?
Allero@lemmy.today · 3 pts · 335d
Because I studied well at school (which is enough as a prerequisite), and also happen to have a major in microbiology, which is related to what we're talking about.
If there are things in particular that you are skeptical about, let me know.
analog_fluffy@lemmy.zip · -1 pts · 335d
It's a stretch. Maybe you are being a bit credulous.
Allero@lemmy.today · 3 pts · 335d
It is, which is why I said "related" as a hedge - and also mentioned that you don't have to be any kind of biologist if you just listened to your biology classes back in the day.
Basic education is enough to understand, in general terms, how it works.
On my end, as a microbiologist, I had extensive training on viruses and the way most of them work is very similar. I can confirm that the vaccine doesn't do anything SARS-CoV-2 itself wouldn't.
So, what makes you skeptical of these vaccines? Or are you trolling around?
dyc3@lemmy.world · 7 pts · 335d
A vaccine is a substance used to stimulate the production of antibodies and provide immunity against a disease. The COVID-19 vaccines do exactly this.
It trains your body to fight the disease. The methods and techniques are different but the fundamentals are still the same. It's ridiculous to think that its permanent genetic modification.
BadlyTimedLuck@lemmy.world · 5 pts · 335d
The only "genetic modification" that I understand happening is the modification to our immune systems being able to fight diseases much better than before. Eventually getting rid of diseases entirely.
But I guess people thought that was stupid, so now we have measles again like its 1953
Allero@lemmy.today · 2 pts · 335d
I think it refers to the delivery of mRNA inside the cells.
Except mRNA does not persist and thereby cannot be seen as a genetic alteration.
kossa@feddit.org · 6 pts · 335d
Traditional vaccines work, because your immune cells learn about the "key" they need, to open up the virus and destroy it.
mRNA is basically just shipping the "keyhole" instead of the whole virus organism for your body to learn the pattern. So no crazy "gene therapy". It is just more precise.
Like, back in the day, people used maps to navigate. Now you use crazy GPS space stuff to do the same. Just better technology for the same end.
analog_fluffy@lemmy.zip · -2 pts · 335d
It's a nice story. I'm on the fence tho
ohshittheyknow@lemmynsfw.com · 2 pts · 335d
More of an analogy then a story. Feel free to do some independent research. Look at some creditable peer reviewed studies. There are mounds of information out there that support both traditional and the newer mRNA vaccines.
analog_fluffy@lemmy.zip · -1 pts · 335d
Yes, do your own research or trust the mob.
Most of us trust the mob.
100_kg_90_de_belin@feddit.it · 4 pts · 335d
You nailed the murder for profit part, but you really missed the mark on everything else
analog_fluffy@lemmy.zip · 1 pts · 335d
There was only one other thing
yistdaj@pawb.social · 1 pts · 335d
By the way, why do you think mRNA vaccines are genetic therapy?