Schizophrenia linked to body’s most prevalent white blood cell

https://news.stanford.edu/stories/2026/05/neutrophils-produce-schizophrenia-linked-c4a-protein

38 points · 6 comments · view on lemmy.world

6 Comments

ushmel@piefed.world · 12 pts · 86d (3 replies)

Interesting, since one of the most effective antipsychotics, clozapine, can nuke neutrophils and lead to opportunistic infections like if you had AIDS.

cockmushroom@reddthat.com · 6 pts · 86d (2 replies)

Sorry if this is a stupid question, but could they set up a system where people with aids can get neutrophils from people with schizophrenia?

Serinus@lemmy.world · 5 pts · 86d

Wait, but.

ushmel@piefed.world · 1 pts · 81d

That wouldn't likely help. The problem isn't too many white blood cells (leukemia) but altered white blood cells (changes in the proteins on the outside of the cells that act like messaging between cells).

HubertManne@piefed.social · 10 pts · 86d

"“Schizophrenia patients’ neutrophils appear to be exhausting their initially plentiful C4A supplies,” she said. “Something, somewhere, is using it up. We don’t know exactly where that’s happening, but we’re hoping to find out.”"

Asidonhopo@lemmy.world · 5 pts · 86d

Does this make it potentially an autoimmune disorder? Interesting discovery, thank you!