Is it? I have no clue about what counts as high but I did try out 125mg gummy bear once as a seasoned smoker and it was 8/10. The high wasn't extreme, it was more focused on "body high" while also lasting 2x as long.
EDIT: By body high I meant that inside "buzzing" feeling, but not losing your mind to the point you laugh for no reason or start doing dumb shit. Somewhat untypical high.
The bioavailability of a suppository instead of edible is insane by comparison. Someone who gets a lower reaction from a ~100mg edible would get similar effects from a suppository less than half that strength because it’s being absorbed by another part of the body - different receptors stimulated and less for it to travel through.
TLDR; if your edible tolerance is high your stomach lining is just more resistant
Also most people who only consume casually are fucking wrecked by 100mg edibles. When I'm not being drug tested I take like one 5-10 mg edible once or twice a month and am hit hard by it. Something in the 20-50 range is normally tolerated by folks who use more than me and have higher tolerance. The only people I know who can do 100 are stoned regularly, often to deal with chronic pain
I rarely get high. Last time was 5mgs gummy and it SENT me, like I forgot how to move for a couple of hours. Back when I was in college and a borderline stoner I probably wouldn't have even have noticed that dosage. Tolerance is a hell of a drug.
I’m that last group, used to need a 100mg two capsule to make it through the day. I’m down to 2 25s a day instead but some of the mental pain still seeps through.
My dose is ~60-80 depending on symptoms but I’m trying to break it into smaller parts to fine tune the effects
Sometimes genetic, sometimes you can shift it with the type (sublingual oil absorbs in the gums, bypasses the liver process which it into 11-Hydroxy thc)
The suppository would do this too, just with a different membrane and easier to have higher doses.
Anecdotals below
•I had one patient who ate a lot of liver after he had to quit drinking, and his edible tolerance dropped
•My edible tolerance dropped when I lost ~100lbs
•a colleague quit all other substances and tolerance dropped there too
I fantasize about massive pristine convenience. Brilliant gold taps, virginal white marble, a seat carved from ebony, a cistern full of Chanel No. 5, and a flunky handing me pieces of raw silk toilet roll. But under the circumstances I'll settle for anywhere.
That is a fucking insane concentration for a suppository.
My weed smoking days are basically over, but uh, I think that that amount would actually make me high for more than an entire day straight, like, probably 2 to 3 days.
35 Comments
ThePantser@sh.itjust.works · 34 pts · 196d
Boofing a joint not enough? Try suppository!
betterdeadthanreddit@lemmy.world · 17 pts · 196d
Boof boof bass.
Evil_Shrubbery@thelemmy.club · 4 pts · 196d
Always on the left-cheek side.
ChicoSuave@lemmy.world · 33 pts · 196d
OriginEnergySux@lemmy.world · 31 pts · 196d
sees THC content
"Yeah I'd shove that up my ass"
Formfiller@lemmy.world · 28 pts · 196d
100 milligrams is a lot I hope you’re not busy for a couple days
REDACTED@infosec.pub · 11 pts · 196d
Is it? I have no clue about what counts as high but I did try out 125mg gummy bear once as a seasoned smoker and it was 8/10. The high wasn't extreme, it was more focused on "body high" while also lasting 2x as long.
EDIT: By body high I meant that inside "buzzing" feeling, but not losing your mind to the point you laugh for no reason or start doing dumb shit. Somewhat untypical high.
EmpathicVagrant@lemmy.world · 7 pts · 195d
The bioavailability of a suppository instead of edible is insane by comparison. Someone who gets a lower reaction from a ~100mg edible would get similar effects from a suppository less than half that strength because it’s being absorbed by another part of the body - different receptors stimulated and less for it to travel through.
TLDR; if your edible tolerance is high your stomach lining is just more resistant
captainlezbian@lemmy.world · 8 pts · 195d
Also most people who only consume casually are fucking wrecked by 100mg edibles. When I'm not being drug tested I take like one 5-10 mg edible once or twice a month and am hit hard by it. Something in the 20-50 range is normally tolerated by folks who use more than me and have higher tolerance. The only people I know who can do 100 are stoned regularly, often to deal with chronic pain
Siethron@lemmy.world · 6 pts · 195d
I rarely get high. Last time was 5mgs gummy and it SENT me, like I forgot how to move for a couple of hours. Back when I was in college and a borderline stoner I probably wouldn't have even have noticed that dosage. Tolerance is a hell of a drug.
EmpathicVagrant@lemmy.world · 2 pts · 195d
This comment is correct dotcom
I’m that last group, used to need a 100mg two capsule to make it through the day. I’m down to 2 25s a day instead but some of the mental pain still seeps through.
My dose is ~60-80 depending on symptoms but I’m trying to break it into smaller parts to fine tune the effects
PacMan@sh.itjust.works · 2 pts · 195d
I know people that can rip 300 -500 mg and it’s no problem. If I take 30 I’m absolutely wrecked and having the best nights sleep every
Corkyskog@sh.itjust.works · 2 pts · 195d
I thought edible tolerance mostly had to do with a genetic marker that dictates how much of an enzyme those peoples liver produced.
EmpathicVagrant@lemmy.world · 4 pts · 195d
Sometimes genetic, sometimes you can shift it with the type (sublingual oil absorbs in the gums, bypasses the liver process which it into 11-Hydroxy thc)
The suppository would do this too, just with a different membrane and easier to have higher doses.
Anecdotals below •I had one patient who ate a lot of liver after he had to quit drinking, and his edible tolerance dropped •My edible tolerance dropped when I lost ~100lbs •a colleague quit all other substances and tolerance dropped there too
Formfiller@lemmy.world · 4 pts · 196d
I just know gummy’s around here come in 5 or 10 mg so 100 would be way too much
some_kind_of_guy@lemmy.world · 4 pts · 195d
Some people have trouble absorbing them. I have the opposite problem. Half of a standard 5mg gummy is more than enough!
undeffeined@lemmy.ml · 6 pts · 196d
Depends hevaily on tolerance levels, no? Or would the fast absortion in the intestine make the high more potent?
bitchkat@lemmy.world · 3 pts · 195d
It's a lot? Who knew.
Pudutr0n@lemmy.world · 23 pts · 196d
how else am I supposed to get high off my ass?
doingthestuff@lemy.lol · 6 pts · 196d
I'm not into butt stuff and sometimes anal jokes get old, but this - take my upvote
DrWhoisit@thelemmy.club · 2 pts · 195d
🥁 That was nice
betterdeadthanreddit@lemmy.world · 18 pts · 196d
Must be a sat-tiva.
starik@lemmy.zip · 8 pts · 196d
Soon to be shat-iva
FoolishObserver@lemmy.world · 7 pts · 196d
In-da-can
EmpathicVagrant@lemmy.world · 5 pts · 196d
Sit-iva, even.
PattyMcB@lemmy.world · 18 pts · 196d
"Good news!"
toofpic@lemmy.world · 16 pts · 196d
If they become popular, there will be just one term more: "Eh, I have weed ass after all the yesterday's fun!"
Luccus@feddit.org · 14 pts · 196d
"Those seem rather small. Do you have one with more girth? No no. The dose can stay the same."
AllNewTypeFace@leminal.space · 14 pts · 196d
RFK Jr. approved
GreenKnight23@lemmy.world · 8 pts · 196d
Asetru@feddit.org · 7 pts · 196d
I fantasize about massive pristine convenience. Brilliant gold taps, virginal white marble, a seat carved from ebony, a cistern full of Chanel No. 5, and a flunky handing me pieces of raw silk toilet roll. But under the circumstances I'll settle for anywhere.
yilian@sopuli.xyz · 2 pts · 195d
sp3ctr4l@lemmy.dbzer0.com · 6 pts · 195d
That is a fucking insane concentration for a suppository.
My weed smoking days are basically over, but uh, I think that that amount would actually make me high for more than an entire day straight, like, probably 2 to 3 days.
maplesaga@lemmy.world · 4 pts · 195d
Its like 10 joints worth. A heroic dose.
normalentrance@lemmy.zip · 4 pts · 196d
I'd try that once
texture@lemmy.world · 3 pts · 196d
finally