Copper drug clears toxic Alzheimer’s proteins and restores memory

Since it's already in clinical trials for ALS and Parkinson's, hopefully testing for Alzheimer's can be done much more quickly than otherwise would be possible.

So, the same failure rate as basically any drug, and many biologics, vaccines.

Yeah but they finally discovered and recalled the fake study that drove them in entirely the wrong direction for decades.

Yeah. The trouble is that pretty much only humans get Alzheimer’s. In order to make a mouse model, we have to induce a disease state that looks like Alzheimer’s, at least to our best understanding. It’s not unreasonable that our mouse model is just not really representative of the actual disease in humans.

Thanks. From the article:

One of its biggest mysteries is also its most distinctive feature: the plaques and other protein deposits that German pathologist Alois Alzheimer linked to the disease in 1906. In 1984, Aβ was identified as the main component of the plaques. And in 1991, researchers traced family-linked Alzheimer’s to mutations in the gene for a precursor protein from which amyloid derives.

I haven’t checked all the sources, but the Aβ model predates the fraudulent papers, which were focused on the Aβ*56 “toxic oligomer” species. However, the model wasn’t looking too hot before hand, and it really resuscitated it. Now yeah, it may have been a zombie

I seem to remeber that the Amyloid plaques are now considered caused by whatever causes Alzheimers, but are not the cause.

I heard this as well

Maybe we’ll finally be able to live out our dreams of acting as captain James T Kirk, wandering the galaxy to have sex with green-skinned women

Maybe we’ll party with that blue skinned guy taking colloidal silver and a bunch of furries, to declare ourselves the Federation

Going to be weird when we've got people salvaging their dead grandparents' foreheads for recycleable metal.

produces a medicine that doesn't work

There's no reason to be needlessly jaded. Those companies would absolutely produce this if it worked, because you'd have to take it forever.

Wdym? If a drug like this were successful, everybody with any markers for Alzheimer's would want to be in on it. They'd make bank for several years, until the patent expires, and then they'd have other methods of extending the patent and prolonging market exclusivity.

Sorry but this is a shit talking point. What drug companies fear is the eradication of an ailment, and particularly by non-pharmaceutical means (i.e. gene therapy).

Even something that's 100% effective in preventing Alzheimer's, would still see a hell of a market.

And if such a drug is possible, then there's the game theory question. Any pharma exec knows that if their company can make a breakthrough medicine...so too could another company. Is it worth it for them to sit on it, only for another company to make the same discovery a year or two later and bring it to market?

This doesn't make sense though, if they have a drug that works, they'll make fucking bank. Pharmaceutical companies would kill for a blockbuster drug like that

Conspiracy theorists alert! Bet you are antivax too.

Capitalism is great for burying all sorts of innovative ideas and holding back progress so profits can be made using sunk investments.

I’m waiting for all the online videos about how it’s actually caused by a parasite, and you can cure yourself with “this one simple trick”

Very little copper in modern pennies, you should probably just supplement zinc. Helps with colds as well.

I wonder how they feel about magnets, lol.

That’s not how drugs work. Even if it worked in humans, they were not treating the mice through skin contact.