Humans May Be Able to Grow New Teeth Within Just 4 Years

https://www.popularmechanics.com/science/health/a69878870/human-new-tooth-regrowth-trials-japan-timeline/

cross-posted from: https://lemmy.bestiver.se/post/832489

Comments

428 points · 121 comments · view on lemmy.world

121 Comments

pyrinix@kbin.melroy.org · 119 pts · 220d (20 replies)
[ removed ]
frongt@lemmy.zip · 60 pts · 220d (3 replies)

A tooth infection can easily spread to your brain and kill you. It's a very short path.

But even if your teeth are just regular bad, that affects how you can eat, and eating is kind of important to living.

adespoton@lemmy.ca · 23 pts · 219d (1 reply)

Research has also shown a link between dental bacteria and heart disease. Not sure if it’s causation or correlation, but keeping your dental microbiome healthy seems to have benefits throughout the body.

Instigate@aussie.zone · 6 pts · 219d

There are larger, more established correlational studies that show a link between dental health and overall physical health as well. There needs to be much more study done but preliminary evidence would suggest that preventive dental care provides for a cheaper overall health cost for a person over their lifetime.

Tollana1234567@lemmy.today · 10 pts · 219d

doesnt need to spread to your brain, just cause sepsis lowering your blood pressure to dangerous levels, or to a major organ and kill you that way.

db2@lemmy.world · 24 pts · 220d

The best description for teeth in the context of insurance that I've ever heard was "luxury bones".

SocialMediaRefugee@lemmy.world · 17 pts · 219d

Gum disease has been linked to heart disease and now there might be a link to dementia due to the bacteria that can enter the bloodstream from the mouth.

Zozano@aussie.zone · 16 pts · 220d (7 replies)

Not to mention a tiny fucking hole in them is one of the the most painful experiences in life which only ends if you see a dentist, wait for it to rot, or rip the tooth out yourself.

And that's not even mentioning how fucked the average persons diet is, it's practically guaranteed to happen eventually, without intervention.

SocialMediaRefugee@lemmy.world · 11 pts · 219d (6 replies)

Then there is the constant risk of biting on something hard and busting a tooth. I've had it happen 3 fucking times.

Redjard@lemmy.dbzer0.com · 2 pts · 219d

Keeping acidic things on your teeth pulls out the flouride making them brittle over time. The flouride added to all kinds of stuff is meant to help with that but the effectiveness is questionable. Better to simply not keep acidic stuff in your mouth too long, and to clean your teeth with your tongue after or swish some water.

Coke is famous for causing brittle teeth.

Zozano@aussie.zone · 0 pts · 219d (4 replies)

Have you tried flossing?

SocialMediaRefugee@lemmy.world · 2 pts · 219d

What does that have to do with biting down on an olive pit or a bit of clam shell?

Tollana1234567@lemmy.today · 2 pts · 219d (2 replies)

doesnt work on the biting surfaces, need to invest an electric or sonic tooth brush for that. and regular cleanings from the dentists. also discourage the usage of whitening toothpaste.

SocialMediaRefugee@lemmy.world · 1 pts · 219d (1 reply)

I have all of those things and get regular cleanings. No whitening toothpaste or treatments.

Tollana1234567@lemmy.today · 1 pts · 219d

regular cleanings and probably mouthwash once in a while, and i use stannous flouride which is better than the regular kind.

nHAP is allegedly used by the flouride free crowd without a significant efficacy since there is more than one company making nHAP, i noticed most of them are obsessed with stuffing it with abrasives, so be wary.

slaacaa@lemmy.world · 7 pts · 219d

Luxury bones

confuser@lemmy.zip · 5 pts · 219d

Just gonna drop this here for anyone that wants to know about the best way to take care of teeth.

https://slrpnk.net/comment/18504970

aesthelete@lemmy.world · 4 pts · 219d

You can pretty much die from bad teeth, like rot and cavities. It is just a matter of when.

Yes, but you're leaving out how bad a problem gum disease is.

Wooki@lemmy.world · 3 pts · 219d

Eyes and skin are not far off if it want for the fact they were replied soon so much. (Re WHS protective goggles , sunscreen)

Tollana1234567@lemmy.today · 2 pts · 219d

mammals pretty much have the short end of the stick as far as teeth and bones goes, we cant replace it often like reptiles can.

Arctic_monkey@leminal.space · 0 pts · 219d

I'm not a fan of insurance companies, but the dental/medical insurance split makes sense. Insurance is fundamentally a risk hedging game. It matters what the risks are. Most medical conditions will only happen to a small percentage of people, so we can all put money into a pool and pay out to the unlucky people who, for example, get cancer. Almost everyone needs some dental work eventually, everyone's teeth wear down. Dental insurance is more like a savings plan than a gamble on rare outcomes. It doesn't make sense to pool those risks together.

Fredselfish@lemmy.world · 70 pts · 220d (5 replies)

Been hearing this claim for 20 years. Let me know where and when I can sign up for the trails.

murmelade@lemmy.ml · 34 pts · 219d (3 replies)

It's always 5 years away though, this one is 4! We're making progress.

epik_kiwi@piefed.blahaj.zone · 12 pts · 219d (1 reply)

24 years is way worse than 5

laughingsquirrel@discuss.tchncs.de · 5 pts · 219d

Hahaha, I'm strangely proud of understanding that joke :D

Canonical_Warlock@lemmy.dbzer0.com · 2 pts · 219d

It was 5 years away last year and now this year it's 4 years away! Why do they keep changing the number !!1!

scarabic@lemmy.world · 2 pts · 219d

Not only does it need to become possible, it needs to become more effective than other treatments like crowns and implants. I think it’s going to be a long time, and even then will only be applicable in limited cases for a long time, and will be really expensive.

radiouser@crazypeople.online · 61 pts · 219d (5 replies)

Swear articles like this get pushed every few years. Let me know when it's a reality I can get at my local dentist.

Canonical_Warlock@lemmy.dbzer0.com · 24 pts · 219d

It's the same study that's been in process for about a decade. It entered human trials last year with those trials expected to take 5 years. Growing teeth is slow. It's not really being pushed, it's just the same reliable hit for various news sites to break out on slow news days.

LastYearsIrritant@sopuli.xyz · 6 pts · 219d (2 replies)

If you only care about technology that's commercially available, why are you on the technology community?

Passerby6497@lemmy.world · 8 pts · 219d

Maybe they care about other technologies that aren't constantly just a couple years away?

radiouser@crazypeople.online · 8 pts · 219d

Just to annoy you, is it working? I hope so.

SaveTheTuaHawk@lemmy.ca · 1 pts · 219d

I get the best biomedical research news from Popular Mechanics.

RememberTheApollo_@lemmy.world · 40 pts · 219d (4 replies)

I’ve been hearing about re-growing teeth for 20 years. Still nothing. It’s right up there with nuclear fusion.

minkymunkey_7_7@lemmy.world · 18 pts · 219d (3 replies)

Cold nuclear fusion. We were quite successful with the hot kind, uncontrolled.

JcbAzPx@lemmy.world · 4 pts · 219d (1 reply)

I mean, we can make fusion happen, but it's not exactly useful outside of turning things into not things anymore.

3abas@lemmy.world · 3 pts · 219d

That's what they said...

AngryCommieKender@lemmy.world · 2 pts · 219d

Not just cold fusion. We are still working on creating hot fusion reactions that are controlled. That honestly makes sense. It's kinda weird that we were able to theorize the uncontrolled reaction of fission, and then used that to create a mostly kinda stable controlled fission reactor.

Prove_your_argument@piefed.social · 32 pts · 220d (2 replies)

[...] will administer the treatment to patients between the ages of 2 to 7 who are missing at least four teeth

Yeah, even if this is approved in some form.. growing new teeth for young children is not the same as for adults. Very weird this is the population they're testing on. I'd think they would be testing on people with 10+ missing teeth in their 40s, 50s, 60s+

[...]these treatments are currently focused on patients with congenital tooth deficiency

Again, not for us.

Sumocat@lemmy.world · 37 pts · 220d

You skipped right past the paragraph before that one describing the adult study that needs to succeed prior to the start of the child study.

Now, scientists will see just how similar, because humans are undergoing a similar trial. Lasting 11 months, this study focuses on 30 males between the ages of 30 and 64—each missing at least one tooth. The drug will be administered intravenously to prove its effectiveness and safety, and luckily, no side effects have been reported in previous animal studies.

Zorque@lemmy.world · 5 pts · 220d

For now

originalucifer@moist.catsweat.com · 31 pts · 220d (6 replies)

i keep seein this story with zero details on application efficacy.. and now i see a thing where theyre giving the drug intravenously??

how do they know it will grow a tooth in a human being and how does it target a lost tooth if not administered directly?

AmidFuror@fedia.io · 33 pts · 220d (4 replies)

The teeth grow everywhere, and you just pull out the ones you don't want.

Pat_Riot@lemmy.today · 14 pts · 220d (2 replies)

I'm reminded of the phrase vagina dentata

Zorque@lemmy.world · 9 pts · 219d (1 reply)

It's a wonderful phrase

Firoaren@sh.itjust.works · 6 pts · 219d

It ain't no passin' craze

originalucifer@moist.catsweat.com · 6 pts · 220d

reminds me of a movie

EldritchFeminity@lemmy.blahaj.zone · 2 pts · 219d

I've seen one of these talked about before, and the mechanism seemed to be in that one that there's a gene in our DNA that triggers us to grow new teeth (that's how we replace our baby teeth with adult teeth), but that that gene turns off after we grow in our set of adult teeth. It's apparently the same gene that allows sharks to grow new teeth. What the drug does is it turns that gene back on, allowing us to grow new teeth to replace lost ones.

This might not be the same study though, as I've also seen one previously years ago that was about a drug that turned on a gene in our teeth to allow them to repair the enamel in them and fill in cavities by putting biodegradable gauze soaked in the drug inside a cavity and letting the tooth do the rest.

Clent@lemmy.dbzer0.com · 26 pts · 219d (1 reply)

Popular mechanics is a terrible source. They post click bait trash like this on a consistent basis.

explodicle@sh.itjust.works · 5 pts · 219d

They've been doing it since before clickbait was even a thing!

phoenixz@lemmy.ca · 23 pts · 219d

No they won't.

This is the same as "humans may live on a mara colony in 10 years!"

No they won't, not even close.

This article is bullshit and so is the entire site, it's all djinn economy, all wishes and fantasy with a clickbait header to make sure you go there to watch the ads to make them money.

tooLikeTheNope@lemmy.ml · 15 pts · 219d (8 replies)

inb4 teeth growing in the most wrong and least expected places

PrimeMinisterKeyes@leminal.space · 4 pts · 219d (5 replies)

A new, horrible torture method just dropped.

wabafee@lemmy.world · 1 pts · 219d (4 replies)

For some reason just thought of teeth in the pussy. Anyway just sharing here cause sharing is caring.

ayyy@sh.itjust.works · 3 pts · 219d

Theres literally a whole movie about this called Teeth.

explodicle@sh.itjust.works · 2 pts · 219d
Evil_Incarnate@sopuli.xyz · 2 pts · 219d (1 reply)

Better than growing a tongue in your asshole.

wabafee@lemmy.world · 2 pts · 218d

Makes me wonder if each poop have distinct flavor lmao.

mcv@lemmy.zip · 3 pts · 219d

This is my main concern. I will believe they can regrow lost teeth, but can they regrow them in the correct shape and location? Teeth can take some weird shapes. We've got millions of years of evolution tweaking exactly where and how they grow, and it still goes wrong sometimes. I suspect messing with that process can lead to Cronenbergian results.

Hupf@feddit.org · 0 pts · 219d

They call her the iron maiden

ayyy@sh.itjust.works · 12 pts · 219d (2 replies)

Popular Mechanics wrote an article saying exactly this same thing like 10 years ago.

explodicle@sh.itjust.works · 2 pts · 219d (1 reply)

Did they? I can't find it.

ayyy@sh.itjust.works · 1 pts · 219d

It may have been Popular Science, the other side of the same rag coin.

DemandtheOxfordComma@lemmy.dbzer0.com · 11 pts · 220d

That's it. Not gonna brush my teeth anymore. Just gonna grow new ones. Maybe sell them. Grow more. Smile big.

FosterMolasses@leminal.space · 11 pts · 219d (6 replies)

Okay but... what kinna teeth we talkin..? Any teeth?

I'd kill for some sharper canines lol

Gsus4@mander.xyz · 7 pts · 219d (2 replies)

like this?

gandalf_der_12te@discuss.tchncs.de · 2 pts · 219d

beware of fanged girls. also, beware of idols. especially, beware of fanged idols.

Sabata11792@ani.social · 1 pts · 219d

Yes.

fishy@lemmy.today · 5 pts · 219d (1 reply)

Mine are so sharp the dentist asked if I wanted them dulled a bit. I of course told him to leave em sharp!

Gsus4@mander.xyz · 8 pts · 219d

Depends on your attack profile and what you're biting: do you want slash, stab or crush damage?

T00l_shed@lemmy.world · 4 pts · 219d

Shark mouth

BradleyUffner@lemmy.world · 11 pts · 219d (9 replies)

Correction: rich humans

lepinkainen@lemmy.world · 7 pts · 219d (8 replies)

Everything is expensive at first, before getting cheaper in the long rub

C4551E@lemmy.blahaj.zone · 5 pts · 219d (3 replies)

yeah except all the things getting more expensive year after year

lepinkainen@lemmy.world · 1 pts · 219d (2 replies)

Like cars? Televisions? Home appliances?

explodicle@sh.itjust.works · 5 pts · 219d

Like dental care

bold_atlas@lemmy.world · 1 pts · 219d

How about sticking to the actual topic: Medicine and dentistry.

Getting a basic filling in 1925 versus the same procedure in 2025.

Regardless of who pays (government, the patient, insurance, etc) which would be more expensive?

bold_atlas@lemmy.world · 2 pts · 219d (3 replies)

By the way:

Basic Model T price in 1909: $825 or $30,000 today.

Basic sedan price in 2025: $30,000

Average price of a car in 2025: $50,000

lepinkainen@lemmy.world · 3 pts · 219d (2 replies)

Cost of model T in 1913: $14,000

Cost of model T in 1916: $9,000

See how the price went down after its 1909 release ? 😁

bold_atlas@lemmy.world · 1 pts · 219d (1 reply)

Find me a new car for $9,000 in the modern day.

FruitLips@lemmy.ml · 2 pts · 219d

Motorcycles can be around that price. Even new.

Kolanaki@pawb.social · 10 pts · 220d (1 reply)

That's a long time to grow a tooth. Can they do anything to speed that up? I'd like a new set of chompers by next week.

Canonical_Warlock@lemmy.dbzer0.com · 4 pts · 219d

I wana be growing and firing teeth out of my jawbone like bullets and become the worlds most horifying superhero/villain. haven't decided which yet

Sharkticon@lemmy.zip · 9 pts · 219d

Rich humans. Us peasants won't be able to.

HugeNerd@lemmy.ca · 9 pts · 219d (1 reply)

Nah. Because

Sweet dreams.

ParadoxSeahorse@lemmy.world · 9 pts · 219d

The reason toddlers have such cute chubby cheeks… because they’re chock full of teeth :D

AwesomeLowlander@sh.itjust.works · 9 pts · 219d

Nothing new in this article, it's just rehashing stuff that's already been announced and talked about since last year.

9488fcea02a9@sh.itjust.works · 8 pts · 220d (4 replies)

Not a dentist, but isnt the root cause of a lot of our dental problems, the loss of gums and the inability of our stupid gums to heal and grow back?

adespoton@lemmy.ca · 8 pts · 219d

I’ve had gum grafts, and they’ve had no difficulty healing and growing back. I’ve also had extra teeth removed and the gums have had no difficulty filling in the gaps. So if all else fails, pull the old tooth, plant the new seed tooth, let the gum heal and then rupture as the new tooth grows out. Should have a nice healthy gum edge again. Although teething as an adult sounds… uncomfortable.

Tollana1234567@lemmy.today · 6 pts · 219d

gum disease, and CARIES, some people are more susceptible to caries than others. anyone with dry mouth will have increased amount of plaque, cavaties. my old dentist said people on chemo have the worst dental health, because of they dry mouth from chemo. other people, such as prognathism,.

orclev@lemmy.world · 4 pts · 219d

Gum disease could lead to tooth loss but the primary way people lose them is through infections due to cavities. The infection weakens the tooth and the jawbone it's rooted in as well as can lead to loss of the root nerve. At a certain point the tooth is too loose or weak and has to be removed to prevent further infection and/or to treat the existing infection.

pool_spray_098@lemmy.world · 2 pts · 219d

I've been loosely following this company's progress for a bit. It doesn't say so in this article, but I think I recall reading that the drug also promotes gum regrowth at the same time.

bstix@feddit.dk · 8 pts · 219d (1 reply)

Can they make it stop too? Not taking any chances on this.

deepus@lemmy.world · 6 pts · 219d

Hopefully not, iv always wanted the powers of a rat!

eleitl@lemmy.zip · 7 pts · 219d

But will I be able to schedule a dentist appointment in four years?

TropicalDingdong@lemmy.world · 6 pts · 220d (1 reply)

Bruh I'm gonna grow so many teeth. I wonder if we'll be able to get crocodile teeth.

Like can I get just one crocodile tooth that hangs over my lip?

CubitOom@infosec.pub · 8 pts · 220d

I want some on my knuckles so I can punch and chew at the same time.


I came here to chew bubble gum and punch Nazis, and I can do both those things with my hands.

deltaspawn0040@lemmy.zip · 6 pts · 219d

My mom lied to me

BonkTheAnnoyed@lemmy.blahaj.zone · 6 pts · 219d

Grow them... where?

...toe teeth!

Edit: my 100th comment!

NatakuNox@lemmy.world · 6 pts · 219d

myrrh@ttrpg.network · 5 pts · 219d
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Vex_Detrause@lemmy.ca · 5 pts · 219d (1 reply)

I will surrogate any of your teeth for a small fee.

bitjunkie@lemmy.world · 5 pts · 219d

Reverse tooth fairy

yannic@lemmy.ca · 4 pts · 219d

I was psyched until I learned it would be a biologic. Those are so bloody expensive and there isn't enough research ruling out potential interactions between multiple biologics to convince my doc to freely prescribe me a second one.

58008@lemmy.world · 3 pts · 219d

Rich humans*

SlartyBartFast@sh.itjust.works · 3 pts · 219d (3 replies)

4 Years? I can grow a new set in 1.

incompetent@programming.dev · 2 pts · 219d (2 replies)

How?

SlartyBartFast@sh.itjust.works · 2 pts · 219d

By making babies, most get their first 6 or so by age one

AngryCommieKender@lemmy.world · 2 pts · 219d

Punching children in the mouth and stealing loose teeth.

/s

robocall@lemmy.world · 3 pts · 219d (2 replies)

My teeth are fine. Call me when someone has a cure for periodontitis!

frongt@lemmy.zip · 2 pts · 219d (1 reply)

Apparently this treatment seems to help gums too, so I suspect it might also help you. But I don't see that they've studied that part yet.

robocall@lemmy.world · 1 pts · 219d

if I could have my gums back, I'd be so happy!

tomkatt@lemmy.world · 3 pts · 219d

I they're gonna take 4 years to grow, I'll just stick with fillings.

Surp@lemmy.world · 2 pts · 217d

And only the fucking rich can afford it. You forgot that part in the title.

chunes@lemmy.world · 2 pts · 219d (8 replies)

If this were to become commercially viable, dentists would move heaven and earth to stop it. Imagine killing 80% of a field with a simple commonplace product.

mctoasterson@reddthat.com · 23 pts · 219d

Doubt it. This is not the type of treatment that is just over the counter. Tooth regrowth would have to be administered and monitored by somebody like an orthodontist. More likely some will just become specialized in it.

Amnesigenic@lemmy.ml · 21 pts · 219d

People who don't have any teeth don't need a dentist, regrown teeth will still get painful cavities or other damage and need fillings or crowns, regrown teeth will probably come in exactly as crooked as your originals and require braces, there's plenty of room for dentists in a world without permanent tooth loss

Passerby6497@lemmy.world · 17 pts · 219d

Are you kidding? Most dentists would love that treatment. You get to improve your patients' dental health, you give them a smile they can be proud of, and you would be the ones administering the treatment.

This will more likely be an upcharge service for cavity fillings and to replace implants and shit.

mcv@lemmy.zip · 12 pts · 219d

Why? More teeth to clean, fill, check and care for.

fluxx@lemmy.world · 2 pts · 219d

Based on how AI might actually replace a bunch of professions, and nobody fighting tooth and nail about it - I don't think so.

RightEdofer@lemmy.ca · 2 pts · 219d (1 reply)
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chunes@lemmy.world · 0 pts · 219d

why are you assuming it would require a physician

SaveTheTuaHawk@lemmy.ca · 2 pts · 219d

Whatever dude, you think this will be free?

Spacehooks@reddthat.com · 1 pts · 219d

Grandma teeth in bowling is going to make less sense in the future.